LuckEner at LUTIAN Global Energy Partner Conference 2026: A New Milestone in Global Growth

TAIZHOU, China, Oct. 28, 2026 /PRNewswire/ -- LuckEner showcased its solar and energy storage solutions, manufacturing capabilities, and service strategy at the LUTIAN Global Energy Partner Conference 2026, held October 12â14 in Taizhou, China. The event brought together more than 200 domestic and international guests from over 60 countries and regions for factory tours, strategic presentations, product launches, and business exchanges.

Building on Industrial Expertise to Advance Green Energy

At the conference, LUTIAN Chairman Changguo Luo outlined the group's strategy for solar and energy storage. Building on its established expertise in motors, electrical controls, power electronics, and energy conversion, LUTIAN has extended its core technological strengths into the sector since 2023, investing more than RMB 300 million in research and development.

LuckEner Product Director Wang Yang showcased the company's portfolio for residential and C&I applications, covering hybrid and on-grid inverters, and battery systems. Designed to accommodate diverse energy needs and grid conditions, these products are complemented by LT Cloud, which enables real-time monitoring, remote diagnostics, intelligent control, and AI-assisted energy management, strengthening system visibility and operational efficiency throughout the energy lifecycle.

Enhancing Service Capabilities and Partner Support

LuckEner also introduced its full-lifecycle service strategy, combining centralized technical expertise with local warehouses, engineers, and service partners. Service commitments include 24/7 response, solutions within 48 hours, issue resolution within 72 hours, and a standard five-year warranty with extensions of up to ten years. The company is also developing digital service tools and partner support systems to improve service transparency and response efficiency throughout the product lifecycle.

A Milestone in Global Business Development

A key highlight of the summit was 10 Million MOU Signing Ceremony, marking an important milestone in LuckEner's customer engagement and creating opportunities for future business growth and market expansion.

Through continued investment in product innovation, manufacturing, and service excellence, LuckEner aims to deliver reliable solar and energy storage solutions for residential and C&I applications, supporting partners across global markets.

About LuckEner

LuckEner provides solar and energy storage solutions for residential and commercial and industrial applications, including inverters, battery systems, and smart energy monitoring. Supported by global R&D resources and advanced manufacturing capabilities, LuckEner develops solutions for diverse markets and grid conditions worldwide.

For more information, visit LuckEner | Solar & Energy Solutions for Homes & Businesses

SOURCE LuckEner

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New Oriental Announces Results for the First Fiscal Quarter Ended August 31, 2026

BEIJING, Oct. 28, 2026 /PRNewswire/ -- New Oriental Education & Technology Group Inc. (the "Company" or "New Oriental") (NYSE: EDU/ 9901.SEHK), a provider of private educational services in China, today announced its unaudited financial results for the first fiscal quarter ended August 31, 2026, which is the first quarter of New Oriental's fiscal year 2027.

Financial Highlights for the First Fiscal Quarter Ended August 31, 2026

- Total net revenues increased by 23.1% year over year to US$1,874.5 million for the first fiscal quarter of 2027.

- Operating income increased by 20.5% year over year to US$374.7 million for the first fiscal quarter of 2027.

- Net income attributable to New Oriental increased by 13.5% year over year to US$273.2 million for the first fiscal quarter of 2027.

Key Financial Results

Operating Highlights for the First Fiscal Quarter Ended August 31, 2026

Michael Yu, New Oriental's Executive Chairman, commented, "We are delighted to start our fiscal year 2027 with strong top line growth of 23.1%, above our current full year guidance range. Revenues from overseas test preparation and consulting business increased by approximately 7.7%. In addition, our domestic test preparation business targeting adults and university students grew by approximately 22.3% year over year, while our new educational business initiatives grew by approximately 24.7% year over year. This quarter, our non-academic tutoring courses reached around 60 cities, attracting approximately 476,000 student enrollments, and our intelligent learning system and devices were adopted across around 60 cities, with approximately 515,000 active paid users. In this new fiscal year, we will continue to deepen the execution of our core strategy, with continuous improvement in teaching and product quality as our primary growth drivers. We are confident that this disciplined approach will enable us to generate healthy and sustainable value over the long term. Alongside our growth momentum, our cost optimization and operational efficiency initiatives have entered a new phase this year and have achieved notable progress. New Oriental Home, our newly established comprehensive customer service platform integrated across all departments, had already served over 1,678,000 families across 69 cities by the end of this quarter. This platform has already begun to demonstrate its ability to enhance customer loyalty and retention and strengthen our cross-selling capabilities. We believe it will further increase customer lifetime value while lowering our overall customer acquisition costs. We remain firmly committed to building a stronger brand and creating enduring value for our customers and shareholders."

Chenggang Zhou, New Oriental's Chief Executive Officer, added, "This fiscal quarter, we continued to execute our strategy of disciplined capacity expansion to balance revenue growth with operational efficiency. Equally important, AI remains at the core of our organizational priorities. This fiscal year, we will maintain measured investment in AI to enhance the competitiveness of our existing products, develop new AI-powered education products that can be commercialized efficiently, and apply AI more broadly to reduce labor costs and improve operating efficiency, while providing stronger support to our staff. In this fiscal quarter, East Buy expanded its private label portfolio to over 1,000 SPUs and its Douyin channel matrix to more than 30 vertical accounts. Leveraging New Oriental's learning center network, East Buy now has four offline experience stores and has developed instant retail capabilities, including one-hour delivery trials in Beijing and Shanghai. For this fiscal year, East Buy will advance its multi-channel strategy, accelerate private label development, refine App membership operations and enhance supply chain efficiency to support sustainable long-term growth."

Stephen Zhihui Yang, New Oriental's Executive President and Chief Financial Officer, commented, "We are pleased to report that, in this fiscal quarter, both our core education business and East Buy recorded year over year expansion in their respective operating margins, primarily attributable to enhanced operational efficiency and improved utilization of our learning centers. Concurrently, East Buy's rapid growth increased its share of total revenue, and this shift in our revenue mix kept our consolidated operating margin at a stable level during this quarter. We view this as an anticipated consequence of scaling new businesses, and we remain confident in the margin trajectory of each business line on a standalone basis. In this fiscal year, we will remain firmly committed to our strategy of pursuing balanced revenue and profit growth, and we will continue to deepen our cost reduction and efficiency enhancement initiatives across key business lines. Through these efforts, we aim to deliver sustainable, healthy growth over the long term while steadily enhancing our profitability."

Update on Shareholder Return for the Fiscal Year 2026

As part of the shareholder return for the fiscal year 2026, the Company announced in October 2025 a share repurchase program (the "2026 Share Repurchase Program"), under which the Company is authorized to repurchase up to US$300 million of its ADSs or common shares over the subsequent 12 months. As of October 27, 2026, the Company had fully utilized the US$300 million repurchase amount authorized under its 2026 Share Repurchase Program for an aggregate of approximately 56.2 million common shares (including common shares represented by ADSs) from the open market.

Update on Shareholder Return for the Fiscal Year 2027

To implement its three-year shareholder return plan adopted in July 2025 for the fiscal year 2027, the board of directors of the Company previously approved an ordinary cash dividend and a new share repurchase program (the "2027 Share Repurchase Program") in July 2026.

The Company today announced that its board of directors has approved an ordinary cash dividend for the fiscal year 2027 of US$0.2 per common share, or US$2.0 per ADS, to be distributed in U.S. dollars in two installments: (i) the first installment, US$0.1 per common share, or US$1.0 per ADS, will be paid to holders of common shares and ADSs of record as of the close of business on November 18, 2026, Beijing/Hong Kong Time and New York Time, respectively; and (ii) the second installment, US$0.1 per common share, or US$1.0 per ADS, will be paid to holders of common shares and ADSs of a record date to be further determined by the board of directors of the Company in due course. The payment date for the first installment is expected to be on or around December 1, 2026 and December 4, 2026 for holders of common shares and holders of ADSs, respectively. The payment date for the second installment is expected to be around six months after the payment date of the first installment. Further details regarding the record date and payment date for the second installment will be announced by the Company in due course.

The aggregate amount of the cash dividend to be paid in two installments is expected to be approximately US$300 million. For holders of common shares, in order to qualify for the first installment of the dividend, all valid documents for the transfer of shares accompanied by the relevant share certificates must be lodged for registration with the Company's Hong Kong branch share registrar, Computershare Hong Kong Investor Services Limited, at Shops 1712-1716, 17th Floor, Hopewell Centre, 183 Queen's Road East, Wanchai, Hong Kong no later than 4:30 p.m. on November 18, 2026 (Beijing/Hong Kong Time). Dividend to be paid to the Company's ADS holders through the depositary bank will be subject to the terms of the deposit agreement.

Pursuant to the 2027 Share Repurchase Program, the Company may repurchase up to US$200 million of its ADSs or common shares over the subsequent 12 months following the board approval. As of October 27, 2026, the Company had not yet repurchased any common shares under the 2027 Share Repurchase Program. The Company's proposed repurchases may be made from time to time in the open market at prevailing market prices, in privately negotiated transactions, in block trades and/or through other legally permissible means, depending on market conditions and in accordance with applicable rules and regulations. The board of directors of the Company will review the share repurchase program periodically, and may authorize adjustment of its terms and size. The Company expects to fund the repurchases out of its existing cash balance.

Financial Results for the First Fiscal Quarter Ended August 31, 2026

Net Revenues

For the first fiscal quarter of 2027, New Oriental reported net revenues of US$1,874.5 million, representing a 23.1% increase year over year. The growth was mainly driven by the increase in net revenues from the Company's new educational business initiatives and East Buy private label products and livestreaming e-commerce business.

Operating Costs and Expenses

Operating costs and expenses for the quarter were US$1,499.8 million, representing a 23.7% increase year over year. The increase was primarily due to the cost and expenses related to the substantial growth in East Buy private label products and livestreaming e-commerce business.

- Cost of revenues increased by 28.1% year over year to US$817.0 million.

- Selling and marketing expenses increased by 30.7% year over year to US$262.2 million.

- General and administrative expenses for the quarter increased by 12.6% year over year to US$420.7 million.

Total share-based compensation expenses, which were allocated to related operating costs and expenses, increased by 31.3% to US$30.6 million in the first fiscal quarter of 2027.

Operating Income and Operating Margin

Operating income was US$374.7 million, representing a 20.

Infoya announced as one of Deloitte's Technology Fast 50 program winners for 2026

OAKVILLE, ON, Oct. 28, 2026 /PRNewswire/ -- Infoya has been recognized by Deloitte's 2026 Technology Fast 50 awards program for its rapid growth, entrepreneurial spirit, and bold innovation.

Infoya leadership attributes the company's impressive growth to its AI-first strategy, continued investment in proprietary AI-powered platforms, and the trust of its clients.

"Being named to the Fast 50 for a second consecutive year reinforces our belief that the future of technology services will be shaped by AI-driven innovation. Enterprises are looking for partners who can help them harness the power of AI to accelerate transformation, improve operational efficiency, and deliver measurable business outcomes. At Infoya, we are embedding AI into everything we do, combining our consulting expertise with proprietary technology to help clients solve complex business challenges and unlock new opportunities. The trust our clients place in us, and their continued expansion of our partnerships, is what drives our growth and motivates us to keep innovating."

The program recognizes Canada's 50 fastest-growing technology companies based on the highest revenue growth percentage over the past four years. Infoya ranks 34th with 665% revenue growth from 2022 to 2025.

"The 2026 Technology Fast 50 winners exemplify the ingenuity, resilience, and ambition that continue to define Canada's technology sector," said Brendan Cooper, National Technology Fast 50 program co-leader. "We are proud to celebrate their achievements and recognize the meaningful impact they are making in communities and markets across the country."

To qualify for the Deloitte Technology Fast 50 ranking, companies must have been in business for at least four years, have a minimum revenue of $50,000 in 2022 and $5 million in 2025, be headquartered in Canada, own proprietary technology, and invest a minimum of 5% of gross revenues in R&D activities that are conducted in Canada.

"This year's winners demonstrate what is possible when vision, talent, and innovation come together. They are tackling complex challenges, unlocking new opportunities, and fueling growth across Canada's technology ecosystem," said Amanda Perran, National Technology Fast 50 program co-leader. "Their success is inspiring the next generation of entrepreneurs and helping to build a more connected, competitive, and innovative future for Canada."

Deloitte's Technology Fast 50 program winners consist of public and private companies in the technology sector that are transforming the industry. The program runs alongside the broader Deloitte North American Technology Fast 500 , and winners are automatically eligible for this elite ranking.

About the Deloitte Technology Fast 50 program

The Technology Fast 50 program is Canada's pre-eminent technology awards program. It recognizes business growth, innovation, and entrepreneurship in three distinct categories: Technology Fast 50, EnterpriseâIndustry Leaders, and Companies-to-Watch. The program also recognizes thriving technology companies in the United States and Canada in partnership with the North American Technology Fast 500 program. Program sponsors for 2026 include RBCx, NRF, TMX, EDC, CCI, Lafond, and The Globe and Mail.

For more information, visit www.fast50.ca.

About Infoya

Infoya is a global IT solutions company specializing in transforming complex challenges into streamlined, AI-powered outcomes. Headquartered in Toronto, with innovation and delivery centers in Chennai (India), San Jose (Costa Rica), and Washington D.C. (USA), Infoya leverages proprietary technology accelerators and full-scale enterprise services to optimize workflows, improve operational efficiency, and drive digital transformation across industries. By combining deep technical expertise with innovative problem-solving, we deliver measurable business impact. We don't just deploy technology; we transform businesses, with AI at the core of everything we build and deliver.

Visit www.infoya.com for more information

SOURCE Infoya

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First joint project launches a broader platform strategy for process orchestration across the clinical trial lifecycle

BERLIN, Oct. 28, 2026 /PRNewswire/ -- Appian (Nasdaq: APPN) and PSI CRO announced today the launch of their first joint AI-powered process orchestration solution. The new offering automates clinical trial site identification and selection across therapeutic areas, indications, and geographies.

The live solution is the first step in a shared vision by PSI and Appian to build a scalable platform that connects automation, AI-powered capabilities, and process orchestration across the full clinical trial lifecycle. Together, the companies are creating a foundation designed to improve efficiency, transparency, and speed across complex clinical trial processes.

AI and process orchestration for complex site selection

Clinical trial site selection is a highly coordinated process involving multiple stakeholders, large volumes of documentation, and parallel activities across countries and regions. The new solution brings previously manual, decentralised steps into a single digital process, from project initiation through the subsequent stages of site selection.

Recognised by Gartner as a Leader in the 2026 Gartner® Magic Quadrant⢠for Business Orchestration and Automation Technologies (BOAT), we believe the Appian Platform provides the foundation for this solution. It identifies and selects the most suitable study sites for sponsors, providing greater end-to-end visibility and enabling faster execution across the site selection process.

The solution goes beyond task automation to orchestrate the end-to-end process, connecting people, data, systems, and AI in a single workflow. It coordinates activities across teams and geographies and automates information and document processing. It also manages routing and exceptions, providing real-time insight into process performance.

The solution integrates with PSI's core systems and data warehouse, as well as Appian's AI and process intelligence capabilities. The integrated solution creates a scalable foundation for faster decisions, greater consistency, and continuous improvement.

Starting point for a long-term platform strategy

The site selection solution puts PSI's platform vision into practice. It combines PSI's focus on predictable clinical trial delivery with Appian's process automation and AI capabilities.

"The AI-powered clinical trial site selection solution is an important step in how we are rethinking and connecting our operational processes," says Kirill Soldatov, Head of Process Improvement at PSI. "PSI is known for our ability to deliver complex clinical trials on time. Building a more connected operational model through automation, AI-powered capabilities, and process orchestration within our existing workflows creates a scalable foundation for more predictable, accurate, and timely site selection worldwide, with the goal to further reduce or eliminate non-enrolling sites and patient enrollment delays."

"This initial project demonstrates the value AI can create when it is embedded in business processes. The solution helps PSI process information faster with automation and manage processes with greater transparency with orchestration. Through our strategic partnership with PSI, we aim to create a flexible, long-term foundation for further automation and innovation," adds Alexander Motie, Regional Vice President DACH & Eastern Europe at Appian.

With the first solution now live, PSI and Appian will build on this foundation by evaluating further use cases to extend AI-powered process orchestration across the clinical trial lifecycle. The goal is to shorten clinical studies and increase predictability, thus introducing new products to market and driving down costs for consumers.

Find out how life sciences companies can use AI automation for faster speed to market here.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements other than statements of historical fact, including statements regarding future product capabilities, strategic plans, and industry growth, are forward-looking. These statements are subject to risks and uncertainties that could cause actual results to differ materially. Appian undertakes no obligation to update forward-looking statements.

About PSI CRO

PSI is a global full-service contract research organisation (CRO), committed to being the best CRO in the world as measured by its customers, investigators, and vendors, and employees. PSI's key operational differentiator is on-time delivery of clinical trials. This metric is still above 90% in 2026.

The company specialises in pivotal clinical trials in oncology, gastroenterology, hematology, immunology, infectious diseases, neurology, among other indications. PSI provides expertise in complex trials at the forefront of precision medicine, including platform and umbrella designs, trials in targeted immunotherapy, radiopharmaceuticals, and cell and gene therapies.

In 2025, PSI celebrated its 30th year of business as the only fully independent and privately owned mid-sized CRO. PSI employs over 3,500 people across 58 countries as of September, 2026.

Global headquarters are in Switzerland at 113a Baarerstrasse, Zug 6300.

For more information, visit www.psi-cro.com.

About Appian

Appian provides AI automation for the most important business processes at the world's largest organisations.

On the Appian Platform, customers build AI-powered processes that accelerate work, reduce cost, and manage risk. Our platform is known for its unique power, reliability, and scale. We've been automating processes for more than 25 years and have proven expertise in enterprise operations. For more information, visit appian.com. [Nasdaq: APPN]

Follow Appian DACH: LinkedIn, Youtube, Instagram, Facebook, and X.

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Streamline your Q3 tax deadline on Monday, November 2, 2026, while managing invoices, purchase orders, and payroll inside the secure, offline ezAccounting platform.

REDMOND, Wash., Oct. 28, 2026 /PRNewswire/ -- Halfpricesoft.com has released critical feature enhancements to its comprehensive ezAccounting software, giving small business owners and accountants an immediate, reliable path to meet the upcoming third-quarter IRS Form 941 electronic filing deadline on Monday, November 2, 2026. By removing the friction of paper-based mailing, ezAccounting allows organizations to process and transmit their quarterly tax documentation straight to federal servers from their desktop while seamlessly tying those records to daily operations like client invoicing and vendor orders.

Download and test ezAccounting today to experience automated, paperless 941 electronic filing before the November 2nd deadline.

"Small businesses need robust, self-contained financial tools that handle daily cash flow and seasonal tax deadlines simultaneously," said Dr. Ge, Founder of Halfpricesoft.com. "ezAccounting delivers full-scale operationsâfrom tracking customer invoices to direct tax filingâin an intuitive interface backed by responsive customer support."

The 2026-2027 ezAccounting suite is currently available at a promotional bundle price 2026 + 2027 Bundle for $319 (regularly $418.00)

Evaluating the software now with our 30-day free trial allows teams to verify compatibility, begin secure data input, and establish a clean financial foundation well ahead of year-end reporting. Start today!

Get the details of the streamlined e941 add-on feature available with ezAccounting purchase.

All-in-One Local Financial Management

While ezAccounting streamlines your quarterly e-filing obligations, the platform is engineered to serve as a complete, independent business accounting ecosystem. It manages day-to-day business accounting without monthly subscription fees through several built-in modules:

- Custom Invoicing & AR: Generate, print, or email professional customer invoices, track accounts receivable, and process incoming customer payments to maintain an accurate cash flow ledger.

- Purchase Orders & AP: Streamline vendor management by creating official purchase orders, tracking inventory arrivals, and managing accounts payable to ensure bills are paid on time.

- Offline Data Privacy: Unlike cloud-based SaaS accounting software, ezAccounting installs locally on your computer. Your financial data, profit margins, and employee information remain completely offline and protected.

- Built-in Check Printing & Payroll: Design and print custom checks on blank check stock for both vendor payments and employee payroll, completely eliminating the ongoing expense of pre-printed checks.

- Comprehensive Tax Compliance: Automatically updates to match shifting federal and state tax codes, ensuring error-free generation of Forms W-2, W-3, 940, 943, and 941.

Eliminate the risk of late filing fines this quarter. Download the 30-day free trial of ezAccounting today with no credit card required, or lock in the 2026-2027 ezAccounting Bundle for just $319 (discounted from $418).

About Halfpricesoft

Halfpricesoft is a premier developer of straightforward, high-efficiency business software solutions, specializing in payroll systems, check printing utilities, and tax compliance automation. Serving over 20,000 small businesses and accounting practices nationwide since 2003, the company focuses on delivering robust, localized software architectures that eliminate high recurring enterprise costs.

SOURCE Halfpricesoft.com

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Weibo Corporation to Report Third Quarter 2026 Financial Results on November 17, 2026

BEIJING, Oct. 28, 2026 /PRNewswire/ -- Weibo Corporation (NASDAQ: WB and HKEX: 9898), a leading social media for people to create, share and discover content, will announce its unaudited financial results for the third quarter 2026 before the U.S. market opens on Tuesday, November 17, 2026. Following the announcement, Weibo's management team will host a conference call from 6 AM â 7 AM Eastern Time on November 17, 2026 (or 7 PM â 8 PM Hong Kong Time on November 17, 2026) to present an overview of the Company's financial performance and business operations.

Participants who wish to dial in to the teleconference must register through the below public participant link. Dial in and instruction will be in the confirmation email upon registering.

Participants Registration Link: https://register-conf.media-server.com/register/BI816d8d5799814de5b22b07a130b7eb28

Additionally, a live and archived webcast of this conference call will be available at http://ir.weibo.com.

About Weibo

Weibo is a leading social media for people to create, share and discover content online. Weibo combines the means of public self-expression in real time with a powerful platform for social interaction, content aggregation and content distribution. Any user can create and post a feed and attach multi-media and long-form content. User relationships on Weibo may be asymmetric; any user can follow any other user and add comments to a feed while reposting. This simple, asymmetric and distributed nature of Weibo allows an original feed to become a live viral conversation stream.

Weibo enables its advertising and marketing customers to promote their brands, products and services to users. Weibo offers a wide range of advertising and marketing solutions to companies of all sizes. Weibo generates a substantial majority of its revenues from the sale of advertising and marketing services, including the sale of social display advertisement and promoted marketing offerings. Weibo displays content in a simple information feed format and offers native advertisement that conform to the information feed on our platform. We are continuously refining our social interest graph recommendation engine, which enables our customers to perform people marketing and target audiences based on user demographics, social relationships, interests and behaviors, to achieve greater relevance, engagement and marketing effectiveness.

Contact:

Investor Relations

Weibo Corporation

Email: [email protected]

SOURCE Weibo Corporation

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Innovative research builds on existing breakthroughs to overcome drug resistance in RET-positive cancers

WASHINGTON, Oct. 28, 2026 /PRNewswire/ -- The 2026 recipients of the RETpositive/LUNGevity Translational Research Award for RET-positive Cancer have been announced by LUNGevity Foundation and RETpositive. The awards support innovative research aimed at advancing treatment options and improving outcomes for people living with RET-positive cancer.

Alterations in the RET gene are known to drive several cancers. RET fusions, created when part of the RET gene joins with another gene, occur in 1% to 2% of non-small cell lung cancers. Changes to the RET gene are also found in thyroid, colon, breast, and other cancers. Currently, two RET tyrosine kinase inhibitors (TKIs) are approved by the US Food and Drug Administration to treat RET-positive cancer. Although these therapies can be effective, tumors eventually evolve to resist treatment and begin to grow again. Overcoming drug resistance is therefore a critical priority for patients with RET-positive cancers.

Through this award mechanism, RETpositive, a patient-led advocacy organization dedicated to raising awareness and advancing research for RET-positive cancers, aims to accelerate high-impact studies that address treatment resistance and transform the future for everyone diagnosed with RET-positive cancer.

"Patients cannot afford to wait. We need to be smart and efficient by supporting only the most promising ideas so they can become lifesaving treatments as soon as possible," said Emily Walthall, RETpositive board member living with stage IV RET-driven lung cancer. "Through our partnership with LUNGevity, we are building novel combination approaches to treatment that are designed to overcome drug resistance in RET-positive cancers."

The recipients of the 2026 RETpositive/LUNGevity Translational Research Award for RET-positive Cancer are:

Researcher: Tejas Patil, MD

Institution: University of Colorado Denver, AMC and DC

Project: Targeting cell cycling vulnerabilities in RET-fusion positive NSCLC

Total Award: $140,000

Drug resistance to RET TKIs is caused by drug-tolerant persister (DTP) cells that adapt and evolve to evade treatment. In this project, Dr. Patil aims to understand how these DTP cells survive and how to eliminate them before resistance develops. There are special cellular pathways that are known to help DTP cells survive. Dr. Patil aims to overcome drug resistance by combining a drug that targets these pathways with a RET TKI. Because the drugs he plans to test are already used in other cancers, this approach could speed the development of effective new treatments for patients with RET-positive lung cancer.

Researcher: Jie Wu, PhD

Institution: University of Oklahoma

Project: Enhancing RET-targeted cancer therapy with antibody-drug conjugates (ADCs)

Total Award: $200,000

Cancer cells often acquire genetic mutations to work around targeted treatments and drive cancer growth. This moving target has made it difficult for researchers to develop enduring cancer treatments. In this project, Dr. Wu will investigate the use of TKIs in combination with FDA-approved antibody-drug conjugates (ADCs) to kill proliferating tumor cells in residual tumors while sparing healthy cells. By targeting multiple mutations simultaneously, this work has the potential to stop drug resistance from developing in RET-positive cancer. If successful, Dr. Wu's research could offer a treatment strategy for RET-positive cancers that offers an enduring treatment benefit for patients.

"We are excited to partner with RETpositive to support this pan-cancer research award focused on overcoming drug resistance in RET-positive cancers," said Upal Basu Roy, PhD, MPH, Executive Director of LUNGevity Research. "Combining existing, approved treatments offers an effective and efficient path toward the development of lifesaving treatments. The impact of these research projects has the potential to be felt across the RET-positive cancer community by bringing the hope of long-lasting treatments to patients and their loved ones."

About RETpositive

RETpositive is a 501(c)(3) patient-driven group that aims to improve the quality of life and life expectancy of RET-positive cancer patients through increased awareness, community support and advocacy, and medical research funding for RET-driven cancer. For more information about RETpositive, please visit www.retpositive.org

About LUNGevity Foundation

LUNGevity Foundation is transforming what it means to be diagnosed and live with lung cancer. While many organizations focus on one aspect of lung cancer, LUNGevity works across research, advocacy, and patient support, because lasting progress requires connecting all three.

As the largest nonprofit funder of lung cancer research in the United States, LUNGevity drives progress in early detection, more effective treatments, and the next generation of researchers. We empower people diagnosed with lung cancer and their caregivers with scientifically vetted information, resources, and community and advocate for policies that improve access to screening, biomarker testing, treatment, and high-quality care for all.

By connecting scientific discovery, patient experience, and advocacy, we help ensure research reflects what patients need, breakthroughs reach the people who can benefit from them, and patient voices help drive meaningful change.

Our vision is a world where no one dies of lung cancer.

Please visit www.LUNGevity.org to learn more.

About Lung Cancer in the US

- About 1 in 19 Americans will be diagnosed with lung cancer in their lifetime.

- More than 229,000 people in the US will be diagnosed with lung cancer this year, with a new diagnosis every 2.3 minutes.

- It is estimated that close to 65% of all new lung cancer diagnoses are among people with no tobacco exposure or only past tobacco exposure.

- More lives are lost to lung cancer than to the next two deadliest cancers (colorectal and pancreatic) combined.

- Only 29.5% of all people diagnosed with lung cancer will survive 5 years or more, but if it's caught before it spreads, the chance of 5-year survival improves to 65%.

SOURCE LUNGevity Foundation

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Auction Direct USA in Raleigh, North Carolina, Offers Professional Oil Change Services for Used Car Owners

RALEIGH, N.C., Oct. 28, 2026 /PRNewswire/ -- Auction Direct USA in Raleigh, North Carolina, offers professional oil change services to help used car owners maintain engine performance, improve reliability and support long-term vehicle health.

Auction Direct USA in Raleigh, North Carolina, offers professional oil change services through its dealership service center to help drivers maintain their vehicles and support long-term engine performance. An oil change involves draining old engine oil and replacing it with fresh oil that lubricates engine components, reduces friction and helps manage heat. Drivers can visit the dealership's website to explore its service center and learn more about available maintenance options.

Importance of Regular Oil Changes

Engine oil plays an essential role in keeping a vehicle running smoothly. Over time, oil collects dirt, debris and other contaminants that can reduce its effectiveness. Regular oil changes help maintain proper lubrication, minimize engine wear and support reliable performance. Fresh oil also helps protect internal engine components from excessive friction and heat. Following the manufacturer's recommended oil change intervals can help drivers maintain engine efficiency and reduce the risk of preventable mechanical problems. Regular maintenance may also contribute to the vehicle's long-term reliability and help owners avoid costly repairs associated with neglected engine care.

Benefits of Dealership Oil Change Services

Choosing a dealership service center for an oil change provides drivers with access to professional maintenance support. Technicians can help identify the appropriate oil specifications and service intervals based on the vehicle's make, model and manufacturer recommendations. Professional oil change services can also provide an opportunity to check essential fluid levels and inspect other components for potential maintenance concerns. Identifying issues early can help drivers address developing problems before they become more serious. Maintaining service records also helps owners track completed maintenance and plan future appointments.

Service Center for Multiple Vehicle Makes and Models

Auction Direct USA features a state-of-the-art service center equipped to service vehicles of all makes and models. This capability allows drivers with different vehicle types to explore maintenance options at one convenient location. Whether a vehicle requires routine oil replacement or other scheduled maintenance, the service team can help owners understand their service needs and determine appropriate next steps. Vehicle-specific oil requirements and maintenance schedules can vary, making professional guidance valuable for drivers seeking to protect their engines. Regular service is particularly important for used vehicles, as consistent maintenance helps owners monitor vehicle condition and address routine upkeep. Staying current with recommended oil changes can support dependable daily driving and help preserve a vehicle's overall condition.

Schedule an Oil Change at Auction Direct USA

Auction Direct USA in Raleigh, North Carolina, provides drivers with access to professional oil change services and automotive maintenance support. Its service team helps vehicle owners understand their maintenance needs and keep their cars operating as intended. Drivers can visit the dealership's website to explore the service center, learn about available maintenance services and inquire about scheduling an appointment.

Media Contact: Tony Kicinski, 844-678-8048, [email protected]

SOURCE Auction Direct USA

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MQTT can move industrial telemetry across network boundaries without giving every IT system direct access to control systems. That outcome depends on the architecture around the broker, clients, identity, and operations—not merely on choosing an encrypted port.

The first security question is: which components must communicate, in which direction, and for what narrowly defined purpose? Answer it before choosing a broker location or writing a firewall request. A secure collection design limits each publisher and subscriber to the connections and topic scope it actually needs.

Treat the broker as a trust boundary, not just a relay

An MQTT broker receives publications, matches subscriptions, and distributes messages. Whether and how it authenticates clients and authorizes their actions depends on the deployment. Its placement determines which systems need a route to it. It does not remove the need to protect the OT sources that publish data or the IT systems that consume it.

A common conceptual pattern is:

OT device or edge gateway

|

| authenticated MQTT connection

v

Broker in an approved OT, DMZ, or controlled service zone

|

| separately authorized subscriber connection

v

Historian collector or IT application

This is not a universal topology. A site may place a broker near sources, in an industrial DMZ, or in another approved service zone based on its threat model, available services, reliability needs, and operating ownership. The important constraint is that a subscriber in IT should connect to an approved broker endpoint; it does not need unrestricted inbound reachability to controllers or the wider OT network.

NIST’s Guide to Operational Technology Security emphasizes that OT security must account for performance, reliability, and safety as well as conventional cybersecurity risk. Use the site’s approved zone-and-conduit design, rather than copying an example broker placement into every plant.

Separate transport protection from client identity and authorization

TLS can provide confidentiality and integrity in transit and let a client validate the server certificate. It does not decide whether a connected client should publish to a command topic, read a whole site, or continue to use a compromised credential.

Build the broker connection policy in layers:

The MQTT specification deliberately leaves the chosen authentication and authorization technologies to the implementation and deployment. It describes security needs such as client authentication, resource authorization, message integrity, and privacy, but broker ACL syntax and enforcement are not standardized. Validate them on the deployed broker.

Use certificate validation deliberately. Accepting any certificate to make commissioning easier removes a core server-identity check. Where mutual TLS fits the site’s identity and lifecycle model, client certificates can authenticate both ends; where managed user credentials are used, protect them in transit, limit their topic scope, rotate them, and remove them promptly when a device or service is retired.

Keep publisher and subscriber permissions separate

One client identity should not receive broad rights merely because it can publish a useful telemetry stream. A gateway that publishes industrial/site-a/line-2/filler-07/telemetry may need no right to subscribe to commands. A historian collector may need to subscribe to approved telemetry patterns but should not publish to operational-control topics.

Define these permissions separately in the broker’s policy model:

- Publish: exact source branches a device or gateway is allowed to send.

- Subscribe: exact telemetry, event, or health branches a collector may receive.

- Administrative access: distinct operator identities for broker configuration, account changes, and audit access.

Avoid #-style broad access policies when a narrow topic filter can express the purpose. The hierarchy matters because it helps ACLs be readable and reviewable, but a topic design alone is not an access-control system. The broker must actually enforce the policy and log failed attempts.

Shared brokers also need ownership rules. Development, test, and production workloads should not rely on easily confused names and permissive credentials. At minimum, separate environments by endpoint, identity realm, or well-governed namespace; confirm that a test client cannot subscribe to production data through an accidental wildcard.

Manage client identities and certificates as operational assets

Give each connection a unique, traceable client identity. Reused IDs make it harder to attribute activity and can cause client-session conflicts. Associate identities with an owner, source system, allowed topic scope, credential type, expiry date, and revocation procedure.

Certificate and credential rotation needs an operational test, not just a policy. Test a new certificate before expiry, confirm the client rejects an untrusted replacement, and rehearse revoking a lost gateway credential. Keep time synchronization healthy: certificate validity, log correlation, and incident analysis all depend on usable clocks.

For TDengine TSDB Enterprise’s documented MQTT ingestion connector, the current configuration supports broker username/password and TLS verification choices including one-way server-certificate verification and mutual TLS. It also requires unique client IDs for clients connecting to the same MQTT address. These controls apply to the connector-to-broker connection; they do not define the broker’s ACL policy or secure every other path. Verify the deployed edition and version against the current MQTT ingestion documentation before relying on a specific option.

Monitor the access path and test denial cases

Logs should let an operator answer: which identity connected, from where, under which certificate or account, which subscription was granted or denied, and which publication was rejected? Correlate broker events with gateway and collector logs, but do not put secrets or full sensitive payloads into logs by default.

Test negative cases in a safe environment: a client with an expired certificate, a publisher attempting an unauthorized topic, a collector requesting an overbroad subscription, and a connection from an unapproved network path. Confirm that the failure is denied, logged, and alerted according to the operating procedure.

For systems collecting industrial history in TDengine TSDB, this design keeps the data route intentional: sources publish only to an approved broker path, collectors authenticate separately, and the historian receives only the data it is authorized to ingest. TLS is an important layer, but the secure outcome comes from the combined design of network exposure, identity, topic authorization, lifecycle management, and monitoring.

KPMG AG Wirtschaftsprüfungsgesellschaft

Automobilmanager erwarten bis 2035 eine neue globale Wettbewerbsordnung

Berlin (ots)

26 Ausgabe des "KPMG Global Automotive Executive Survey" zeigt: Technologie entscheidet künftig über Marktführerschaft, während China seinen Einfluss in der Automobilindustrie weiter ausbaut.

- 51 Prozent der Führungskräfte erwarten, dass Software und digitale Technologien bis 2035 zum wichtigsten Differenzierungsmerkmal ihres Unternehmens im Wettbewerb werden.

- 49 Prozent bezeichnen ihre softwaredefinierten Produkte und Over-the-Air-Funktionen bereits als etabliert oder fest verankert.

- Nur 36 Prozent der KI- und Softwareinitiativen wurden erfolgreich über die Pilotphase hinaus skaliert.

- 92 Prozent der Unternehmen benötigen mindestens zwölf Monate, um eine neue KI-, Digital- oder Softwarelösung unternehmensweit einzuführen.

- 57 Prozent der Führungskräfte im asiatisch-pazifischen Raum berichten von erheblichen Investitionen in KI und neue Technologien, gegenüber 52 Prozent in Europa und 48 Prozent auf dem amerikanischen Kontinent.

- Fast die Hälfte der Führungskräfte erwartet, dass bis 2035 sechs der zehn größten Automobilhersteller der Welt ihren Hauptsitz in China haben werden.

Software und digitale Technologien werden zum entscheidenden Wettbewerbsfaktor in der Automobilindustrie. Zugleich gehen Führungskräfte zunehmend davon aus, dass China künftig eine führende Rolle in der Branche spielen wird. Das zeigt die 26. Global Automotive Executive Survey von KPMG International. Für die Studie wurden weltweit 775 Führungskräfte aus der Automobilindustrie befragt. 51 Prozent erwarten, dass Software und digitale Technologien bis 2035 zum wichtigsten Differenzierungsmerkmal ihres Unternehmens im Wettbewerb werden. 48 Prozent rechnen zudem damit, dass bis dahin sechs der zehn größten Automobilhersteller der Welt ihren Hauptsitz in China haben werden.

Diese Erwartungen entstehen vor dem Hintergrund tiefgreifender Umbrüche, die die Wettbewerbslandschaft der Branche gleichzeitig verändern. Die Ergebnisse zeigen, dass sich die Führungskräfte auf ein Jahrzehnt überlagernder Veränderungen einstellen: Technologie, Geopolitik, Nachhaltigkeit, operativer Druck, Kundenerwartungen und neue Geschäftsmodelle wirken gleichzeitig und mit vergleichbarer Intensität auf die Branche ein. Das Zusammenwirken dieser Umbrüche macht Transformation zugleich von einem zeitlich begrenzten Programm zum dauerhaften Betriebsmodell der Branche: 52 Prozent stimmen der Aussage zu, dass kontinuierliche Transformation inzwischen zur Normalität gehört.

"Führungskräfte in der Automobilindustrie müssen derzeit mehrere grundlegende Veränderungen gleichzeitig bewältigen - von Technologie und Geopolitik bis hin zu veränderten Kundenerwartungen und neuen Geschäftsmodellen. Diese Entwicklungen greifen zunehmend ineinander und erfordern oft dieselben Ressourcen und dieselbe Aufmerksamkeit des Managements. Unternehmen, denen es am schnellsten gelingt, Technologie in Kundennutzen zu übersetzen und zugleich flexibel auf unterschiedliche Märkte zu reagieren, werden die nächste Entwicklungsphase der Branche anführen", sagt Andreas Ries, Global und Deutschland Head of Automotive bei KPMG.

Technologie ordnet den Wettbewerb in der Automobilindustrie neu

Der Wettbewerb verlagert sich in Richtung KI, fortschrittlicher Fahrerassistenzsysteme, intelligenter Cockpits, softwaredefinierter Fahrzeuge und vernetzter Dienste. 51 Prozent erwarten, dass Software und digitale Technologien bis 2035 zum wichtigsten Differenzierungsmerkmal ihres Unternehmens im Wettbewerb werden. 49 Prozent bezeichnen ihre softwaredefinierten Produkte und Over-the-Air-Funktionen bereits als etabliert oder fest verankert. 42 Prozent sehen einen vergleichbaren Reifegrad bei ihrer übergreifenden Strategie für softwaredefinierte Fahrzeuge.

Die Umsetzung bleibt jedoch die entscheidende Lücke. Im Durchschnitt wurden nur 36 Prozent der KI- und Softwareinitiativen über die Pilotphase hinaus skaliert und unternehmensweit eingeführt. 92 Prozent der Unternehmen benötigen mindestens zwölf Monate, um eine Digital-, Software- oder KI-Lösung im gesamten Unternehmen auszurollen. Mehr als ein Drittel braucht dafür über zwei Jahre.

Auch regional entwickeln sich die Kompetenzen unterschiedlich schnell. 57 Prozent der Führungskräfte im asiatisch-pazifischen Raum berichten von erheblichen Investitionen in KI und neue Technologien, gegenüber 52 Prozent in Europa und 48 Prozent auf dem amerikanischen Kontinent. Der asiatisch-pazifische Raum führt bei der Integration von autonomem Fahren und Fahrerassistenzsystemen mit 52 Prozent. Europa und der amerikanische Kontinent liegen jeweils bei 44 Prozent. Bei der KI-Governance erreicht die Region 50 Prozent, verglichen mit 45 Prozent in Europa und 39 Prozent auf dem amerikanischen Kontinent.

Technologieführerschaft wird jedoch längst nicht mehr allein durch interne Kompetenzen bestimmt. Mit der Weiterentwicklung von Automobilsoftware, KI und vernetzten Diensten erkennen Unternehmen zunehmend, dass ihre künftige Wettbewerbsfähigkeit nicht nur von Technologieinvestitionen, sondern ebenso von der Stärke ihrer Ökosysteme abhängt. Der Anteil der Wertschöpfung, der durch externe Partnerschaften und Ökosysteme ermöglicht wird, dürfte innerhalb von drei Jahren von heute 30 Prozent auf 44 Prozent steigen.

Auch Vertrauen wird zu einem wichtigen Differenzierungsmerkmal: Die Hälfte der Führungskräfte geht davon aus, dass das Vertrauen in digitale und vernetzte Funktionen in den kommenden drei Jahren maßgeblich darüber entscheiden wird, welche Unternehmen sich durchsetzen.

China rückt ins Zentrum der Automobilindustrie

Die technologiegetriebene Verschiebung der Wertschöpfung prägt auch die Erwartungen der Führungskräfte an eine neue globale Wettbewerbsordnung. Ein wachsender Anteil der Befragten geht davon aus, dass China in der weltweiten Automobilindustrie eine noch einflussreichere Rolle spielen wird. Fast die Hälfte erwartet, dass im Jahr 2035 sechs der zehn größten Automobilhersteller ihren Hauptsitz in China haben werden.

Die Analyse verweist auf Chinas wachsende Kompetenzen bei Elektrifizierung, Software und digitaler Innovation. Damit gewinnt das Land bei technologiegetriebenen Wertschöpfungsfeldern der Automobilindustrie weiter an Einfluss. Die Erwartung einer stärkeren chinesischen Präsenz ist Teil einer breiteren Verlagerung hin zu technologiegetriebener Wertschöpfung im asiatisch-pazifischen Raum.

Der Bericht zeigt außerdem, dass sich die Wertschöpfung über das Fahrzeug hinaus erweitert. Führende Unternehmen nutzen ihre Kompetenzen, um Chancen unter anderem in den Bereichen Energiespeicherung, Verteidigungsanwendungen, vernetzte Dienste und Finanzdienstleistungen zu erschließen.

"Die Wettbewerbslandschaft der Branche wird neu geordnet. Technologie verändert, was Kunden wichtig ist, wie sich Unternehmen differenzieren und wo künftig neue Ertragspotenziale entstehen können. Chinas wachsender Einfluss ist eines der deutlichsten Signale für diesen Wandel. Erfolg hängt jedoch von mehr ab als von Standort oder Größe: Entscheidend sind die Fähigkeit, Technologien wirksam einzusetzen, die richtigen Öko-systeme aufzubauen und sich an zunehmend unterschiedliche Märkte anzupassen", sagt Nicolas Nowicki, Partner bei KPMG Frankreich und Head of Automotive für die EMA-Region.

Pressekontakt:

KPMG AG

Wirtschaftsprüfungsgesellschaft

Clemens Reisbeck

+49 89 9282 1722

creisbeck@kpmg.com

www.kpmg.com/de

Original-Content von: KPMG AG Wirtschaftsprüfungsgesellschaft, übermittelt durch news aktuell