EU – October 27, 2026 -- The Joint Committee of the European Supervisory Authorities (EBA, EIOPA and ESMA) has published its Annual Work Programme for 2027. It lists digital operational resilience, technological innovation, sustainable finance, securitisation and cross-sectoral risk monitoring as the five key priorities for the EU financial sector.

European Union – October 27, 2026 -- The number of retail clients receiving cross-border investment services in the EU/EEA rose 47% in 2025 from 2024 to about 15.5 million, according to the European Securities and Markets Authority (ESMA).

That is almost twice the 2023 level. ESMA compiled the annual analysis with national competent authorities (NCAs), using data from investment firms across 30 jurisdictions.

European Union – October 27, 2026 -- National authorities across the European Economic Area (EEA) imposed more than 950 administrative sanctions and measures in 2025, with administrative fines totaling almost €82 million, according to the third Sanctions Report from the European Securities and Markets Authority (ESMA).

The number of sanctions and measures was stable compared with the past two years. The report also records an increased use of settlements.

European Union – October 27, 2026 -- The European Securities and Markets Authority (ESMA) has updated its transparency manual with new guidance on identifying over-the-counter (OTC) derivatives subject to transparency requirements and on applying the tick-size regime.

ESMA specifies how OTC derivatives reference data must be supplied

The update clarifies how identifying reference data for OTC derivatives should be provided for transparency purposes. ESMA aims to make the data reported to, and published through, the consolidated tape more consistent.

European Union – October 27, 2026 -- The EU will switch to T+1 settlement on 11 October 2027, and the European Securities and Markets Authority (ESMA) says the regulatory framework is now complete. ESMA is calling on market participants to finalise technical preparations, assess readiness across their entire ecosystems and start testing across the trading and settlement chain as soon as possible.

European Union – October 27, 2026 -- The European Securities and Markets Authority (ESMA) has finalised its revised Market Abuse Regulation (MAR) guidelines on delaying the disclosure of inside information, adding five legitimate interests that issuers can cite to justify a delay.

EU – October 27, 2026 -- The European Securities and Markets Authority (ESMA) has defined the conditions that providers and users of post-trade risk reduction (PTRR) services must meet for certain OTC derivative transactions to be exempt from the clearing obligation under EMIR 3.

European Union – October 27, 2026 -- The European Securities and Markets Authority (ESMA) has withdrawn or amended several Questions and Answers (Q&As) covering market structure under MiFID II, the Market Abuse Regulation (MAR) and the Short Selling Regulation (SSR), removing guidance it considers outdated, duplicative or no longer relevant.

PONTE VEDRA, Fla. – October 27, 2026 -- Cadrenal Therapeutics (Nasdaq: CVKD) reached agreement with the FDA on the primary endpoint and placebo-controlled design of its Phase 3 registration study of CAD-1005, a first-in-class 12-lipoxygenase (12-LOX) inhibitor for heparin-induced thrombocytopenia (HIT). The agreement came at a Type D meeting held July 28, 2026.

Europe – October 27, 2026 -- The European Banking Authority (EBA) has opened a call for papers for its 13th Annual Research Workshop, "Boundaries of Banking Regulation", with a submission deadline of Friday 5 July 2024.